1. General clinical data (types of pigments, total number of cases and selection of cases):
Subject: Facial skin has pigments, including epidermal pigments, dermal pigments, and artificial pigments.
Test content: The therapeutic effect of S1070 on patients with pigment.
Experimental purpose: to verify the therapeutic effect of the product through experiments.
Experimental parts: face, neck, body parts containing pigments and other parts.
Treatment part in this case: cheekbones to temples on the face, ABNOM on the cheekbones
2. Things used in the treatment
S1070 machine, camera, skin repair cream, 75% alcohol, repair factor,and mask etc
3. Test method
Before treatment, choose the skin type (type I-VI), and select the corresponding probe, wavelength and energy according to the condition of the pigment. When performing the treatment for the first time, it is better to do it with low energy. If the patient is mixed with melasma, low energy and large spot treatment method is required.
Treatment Steps:
1. Cleanse face and take photos before treatment.
2. Choose treatment tip for different skin pigment.
3. Wrap hair of the patient. Both doctor and patient should be under good protection of the eyes(patient uses blinder and doctor wears protective glasses).
4. Doctor should wear mask and disposable gloves.
5. Doctor should keep checking at the treating area and see how the skin changes and stop when see the clinical endpoint (the below taboo crowds and treatment skills are for doctors reference ).After treatment attention need to be told to the patient.
|
Treatment time |
Energy |
Frequency |
Spot size |
Tip |
Treatment method |
After treatment care |
|
1/1 |
0.6 |
5 |
5 |
1064nm |
After treatment, the epidermal spots are white and the skin appears Sha or slightly oozes blood. |
Pay attention to sun screen, and use a moisturizing mask (at least three days or more). on a diet and not eat spicy food. Do not deduct the scab after it has formed. |
4. Treatment data
1. When treating AQMOB it is important to tell if the patient has melasma and if yes the treatment method will be different.
2. Can use the IPL machine to treat the AQMOB before laser treatment and must use low IPL energy or it will flirts the melasma.
3. Can apply the Tranexamic acid during the whole treatment or use the mesogun to inject product Inhibit the activity of tyrosinase.
4. Use RF machine to accelerate the blood circulation and metabolism ability of the skin.
5. Use EGF after the laser treatment to accelerate the skin recovery.
5. Treatment result pictures
First treatment
Second treatment
Third treatment
Fourth treatment
Fifth treatment
Skin reaction after treatment：—skin will be reddish and some of part with dark pigment will be bruised or mild bleeding.
If the treatment part has been treated with serous bleeding and the treatment interval can be prolonged depending on the skin recovery.
6. Treatment skills
1. Keep the treatment tip 2~3cm from skin, when hear the voice of blasting and treated area gets frosty white, then keep this parameter and distance to do the treatment.
2. If not, then try higher distance between skin to find the best blasting distance.
3. If all above tried but make no sense, then set the energy parameter higher a little bit, or change the spot size smaller a little.
Clinical skin changes
when treated area gets frosty white immediatly, then should move to another area for treatment. Red, swollen, hot, slightly painful, or mild-bleeding after surgery are normal skin reactions
7. Possible adverse events and side effects found in clinical trials during the treatment
1. skin reddish and bleeding is the normal skin reaction.
Solution：Apply cold compress or clod wind machine right after the treatment and stop till the skin reddish is gone
2. Blisters, crusts, hyperpigmentation are postoperative complications after the treatment.
Solution：External use of drugs to eliminate pigmentation (kojic acid cream), antipruritic drugs (Wuji ointment) or oral (vitamin C, vitamin E, anti-allergic drugs, etc.)
8. Clinical trial effect analysis
1. When the patient has no melasma in the facial part and treating with stronger energy intensity will achieve a better result when comparing with the time using low laser energy.
2. When the pigment has been reduced dramatically and combing with IPL treatment will achieve better result and when the pigment is dark. Please do not use the IPL treatment with dark pigment or it will cause bubbles on the skin.
3. Treatment on the dermal skin pigment it is better to treat the pigment till there is mild skin bruise and mild bleeding.
9. Clinical trial conclusion：
Conclusion:
1. By the principle that High energy that instantaneously emitted by laser is selectively absorbed by pigments. Light energy was converted into heat and the pigments will be shattered into tiny particles instantly.which can indeed remove pigments on the dermal skin.
2. Because the normal skin has no absorption for the laser and only melanin will absorb the laser so the treatment is safe with no side effects。
10. Discussion:
1. Melanin is mainly formed by the chemical reaction of tyrosinase(TYR) in melanin particles, and melanin moves through layers of cellular metabolism. When the metabolic function of the skin is less than the rate of pigmentation, spots are formed.
2. During summer it is better not to expose to the sun directly or it will cause the pigment worsen.
3. When treating the dermal skin pigment and 532nm wavelength is not suitable.
Post time: Feb-21-2022
