Acne is a chronic inflammatory skin disease that occurs mostly in adolescents and commonly occurs on the face, chest, and back. The main pathogenic factors are closely related to the excessive secretion of sebaceous glands, the obstruction of hair follicle ducts, the proliferation of Propionibacterium acnes, and the increased expression of inflammatory factors.
The skin lesions of severe acne are large and can easily lead to permanent hyperplastic or depressed scars, which can seriously affect the patient's appearance. Adolescent patients are especially prone to carry a heavy psychological burden, which in turn affects their learning status and character development.
Most of the conventional clinical drug treatments have slow onset and long courses of treatment, and some have concerns about adverse reactions such as drug resistance and liver damage. The emerging photodynamic therapy has become the first choice for many patients with moderate to severe acne.